I don't see why waiting for commits is going to prevent you from reaching that target -- commit is extremely fast in Oracle. It seems an odd thing to focus on -- I'd be thinking more about the need to use low latency connections and bulk binding.

Like davey says, which ones do you know about? And where are you going to place your logic? If you want to reduce roundtrips to the database then put your logic into PL/SQL packages and call them with OCI.