This is a wide open question! What dB version? Ur thinking RMAN right?

Will you write an RMAN script controlled by O/S or OEM and go to disk or directly to tape? Or will you customize the sample scripts by Veritas, create a policy that interfaces with RMAN, thereby being controlled by Netbackup? In the later you will need to install and configure Netbackup's Oracle extension.

What I do is control RMAN through a UNIX script cron, go directly to disk and that image is immediately copied to tape via a Netbackup policy. HTH