Yes, but without data from this datafile:
Code:
SQL> set linesize 300
SQL> select segment_name, tablespace_name,relative_fno from dba_segments where owner='SCOTT';

SEGMENT_NAME                                                                      TABLESPACE_NAME                RELATIVE_FNO
--------------------------------------------------------------------------------- ------------------------------ ------------
DEPT                                                                              USR                                       4
EMP                                                                               USR                                       4
BONUS                                                                             USR                                       4
SALGRADE                                                                          USR                                       4
PK_DEPT                                                                           USR                                       4
PK_EMP                                                                            USR                                       4

6 rows selected.

SQL> alter database datafile 4 offline;

Database altered.
Code:
C:\Temp>exp scott/tiger

Export: Release 9.2.0.1.0 - Production on Sun Jan 4 22:07:58 2004

Copyright (c) 1982, 2002, Oracle Corporation.  All rights reserved.


Connected to: Oracle9i Enterprise Edition Release 9.2.0.1.0 - Production
With the Partitioning, OLAP and Oracle Data Mining options
JServer Release 9.2.0.1.0 - Production
Enter array fetch buffer size: 4096 >

Export file: EXPDAT.DMP >

(2)U(sers), or (3)T(ables): (2)U > 3

Export table data (yes/no): yes > yes

Compress extents (yes/no): yes > no

Export done in CL8MSWIN1251 character set and AL16UTF16 NCHAR character set

About to export specified tables via Conventional Path ...
Table(T) or Partition(T:P) to be exported: (RETURN to quit) > emp

. . exporting table                            EMP
EXP-00056: ORACLE error 376 encountered
ORA-00376: file 4 cannot be read at this time
ORA-01110: data file 4: 'D:\ORA92\DATABASE\USR01.DBF'
Table(T) or Partition(T:P) to be exported: (RETURN to quit) > dept

. . exporting table                           DEPT
EXP-00056: ORACLE error 376 encountered
ORA-00376: file 4 cannot be read at this time
ORA-01110: data file 4: 'D:\ORA92\DATABASE\USR01.DBF'
Table(T) or Partition(T:P) to be exported: (RETURN to quit) >

Export terminated successfully with warnings.

C:\Temp>exp scott/tiger

Export: Release 9.2.0.1.0 - Production on Sun Jan 4 22:09:31 2004

Copyright (c) 1982, 2002, Oracle Corporation.  All rights reserved.


Connected to: Oracle9i Enterprise Edition Release 9.2.0.1.0 - Production
With the Partitioning, OLAP and Oracle Data Mining options
JServer Release 9.2.0.1.0 - Production
Enter array fetch buffer size: 4096 >

Export file: EXPDAT.DMP >

(2)U(sers), or (3)T(ables): (2)U > 3

Export table data (yes/no): yes > no

Compress extents (yes/no): yes > no

Export done in CL8MSWIN1251 character set and AL16UTF16 NCHAR character set
Note: table data (rows) will not be exported

About to export specified tables via Conventional Path ...
Table(T) or Partition(T:P) to be exported: (RETURN to quit) > emp

. . exporting table                            EMP
Table(T) or Partition(T:P) to be exported: (RETURN to quit) > dept

. . exporting table                           DEPT
Table(T) or Partition(T:P) to be exported: (RETURN to quit) >

Export terminated successfully without warnings.