Why don't you just try an experiment?

Make a big file. Make a copy of the big file. Copy the big file onto the end of the copy again and again until it breaks.

Check it on your file systems to make sure they are all the same.

That way you don't get misled by an answer that depends on the local configuration of someone else's file systems.

My system has a number of file systems that were added over the past few years and have not been rationalized in some time. This morning I discovered a file system that had not been converted to handle 2+ GB files. I was taken by surprise since I don't often use 2+ GB files but haven't run into any problems with them for some time.