Please be more specific about your configuration: are you planning on using an application or just clients, if application, is is web-based, is it using oracle tools, is in 3rd party or is it in-house developed... does it use Java etc. Because connectivity and the whole setup will depend on what you actually want to connect to your database. MTS is very useful when you just have lots of network activity, if you use just a jav-based apps you can set it up without MTS.
Alla S. Pfauntsch
"Life is what happens while you are planning something else".