I think yes, because with _db_handles_cached =0 you are actually setting off the buffer handles, i.e, you have no handles cached per process. Thus your performance my suffer.
Very good input. So you mean to say that "event="10262 trace name context forever, level 10000" solves the memory leak problem. Why I am asking this, I had this problem, and I set both the parameters. It is Ok now. Since _db_handles_cached=0 hurts the performance, no meaning to set this parameter. Some times exploring too many documents also creates problems? am I correct?