Actually, the word I got from Oracle support was to upgrade to 220.127.116.11, but not to go to 18.104.22.168 as that patch had several large memory leak problems. This is scheduled to be fixed in the next major release, they said.
Yes, I did encounter a problem once. with migrating from 8.0.4 to 8.1.6. From that point on, I don't want to take any chances, because, what happen was when I spoke to oracle, I mentioned that I migrated to 22.214.171.124, their first question was how did you migrated, and after hearing my story, their reply was go back and start at the base and then apply the patch. IT all worked after that and I was happy.
From that time, I'll spend some time more in following things step by step, rather than going back to re-do things with the agonny